Fenway Health begins antibody trial for housemates of people with COVID

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Photo fenwayhealth.org

Boston-based Fenway Health, one of the nation’s foremost health centers for LGBTQA people, is now a clinical trial site for an antibody study to prevent COVID-19 disease among housemates of recently diagnosed people.

“Fenway Health is excited to be part of the COVID Prevention Trial Network’s evaluation of Regeneron’s monoclonal antibody combination for the prevention of COVID-19 disease,” said Dr. Kenneth H. Mayer, Fenway’s medical research director and co-director of The Fenway Institute.

“The study will enroll individuals whose household members have been infected with SARS-CoV-2, the virus that causes COVID-19, and can provide important insights about this promising new prevention modality. Given our decades of studies focusing on pre- and post-exposure prophylaxis to prevent HIV infection, this trial builds on our extensive experience in infection prevention research.”

The study, explains Fenway’s press release:

will examine the efficacy of REGN-COV2, Regeneron Pharmaceuticals’ investigational double antibody combination for the prevention of COVID-19. This Phase 3 trial will evaluate REGN-COV2’s ability to prevent infection among uninfected people who have had close exposure to a COVID-19 patient, such as the patient’s housemate or partner. It is led by Regeneron and sites part of the COVID-19 Prevention Network (CoVPN) are participating in the trial. Supported by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), the CoVPN aims to enroll thousands of volunteers in large-scale clinical trials testing a variety of investigational vaccines and monoclonal antibodies intended to protect people from COVID-19.

The study is one of several Phase 3, randomized, placebo-controlled, double-blind clinical trials testing whether experimental monoclonal antibodies can prevent infection of SARS-CoV-2 coronavirus now enrolling healthy adults at clinical trial sites in the United States. Many of the trial sites and study investigators are part of the CoVPN. The trials are enrolling adults who are at risk of infection due to close contact to persons with SARS-CoV-2 infection at work or home. 

For more information about COVID-19 research at Fenway Health, call (617) 927-6450 or send an email to bethechange@fenwayhealth.org.

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